Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …

In the most recent decades, oxaliplatin has been used as a chemotherapeutic agent for
colorectal cancer and other malignancies as well. Oxaliplatin interferes with tumor growth …

Current treatments for inflammatory bowel disease (IBD) are often inadequate due to limited
efficacy and toxicity, leading to surgical resection in refractory cases. IBD's broad and …

Chemotherapy-induced peripheral neurotoxicity (CIPN) is a common, sometimes dose-
limiting side effect of neurotoxic chemotherapy. Treatment is limited because its …

Chemotherapy is the most common treatment for malignant tumors. However, chemotherapy-
induced gastrointestinal toxicity (CIGT) has been a major concern for cancer patients, which …

Oxidative stress is increasingly recognized as a central player in a range of gastrointestinal
(GI) disorders, as well as complications stemming from therapeutic interventions. This article …

Cisplatin, carboplatin and oxaliplatin represent the backbone of platinum therapy for several
malignancies including head and neck, lung, colorectal, ovarian, breast, and genitourinary …

Colitis-associated cancer (CAC) is a subtype of inflammatory bowel disease (IBD)-
associated colorectal cancer. Huoxiang Zhengqi (HXZQ) is a classical Chinese herbal …

Oxaliplatin (OXL) is the first line treatment therapy for gastrointestinal (GI) cancers and often
combines with other chemotherapy. However, few reports have studied on its GI toxicity …

BGP-15 is a new insulin sensitizer drug candidate, which was developed by Hungarian
researchers. In recent years, numerous research groups have studied its beneficial effects. It …