MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

MicroRNAs (miRNAs) are small RNA molecules, which can interfere with the expression of
several genes and act as gene regulator. miRNAs have been proved as a successful …

MicroRNAs (miRNAs) involved in key signaling pathways and aggressive phenotypes of
osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 …

Osteosarcoma (OS) is a primary malignant bone tumor with high morbidity that principally
emerges in children and adolescents. Presently, the prognosis of OS patients remains poor …

Osteosarcoma (OS) is the most common pediatric malignant bone tumor, and occurrence of
pulmonary metastasis generally causes a rapid and fatal outcome. Here we aimed to …

Epigallocatechin-3-gallate (EGCG), the most abundant and active polyphenol in green tea,
has been demonstrated to have anticancer effects in a wide variety of human cancer …

MicroRNAs (miRNAs) decrease the expression of specific target oncogenes or tumor
suppressor genes and thereby play crucial roles in tumorigenesis and tumor growth. To …

Abstract Introduction Circulating microRNAs (miRNAs) are easily accessible and have
already proven to be useful as prognostic markers in cancer patients. However, their origin …

Despite the availability of multimodal and aggressive therapies, currently patients with
skeletal sarcomas, including osteosarcoma and chondrosarcoma, often have a poor …

The development of miRNA-based therapeutics represents a new strategy in cancer
treatment. The objectives of this study were to evaluate the differential expression of …