COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment

K El Karoui, AS De Vriese - Kidney International, 2022‏ - Elsevier
The COVID-19 pandemic has profound adverse effects on the population on dialysis.
Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality …

Long-term interplay between COVID-19 and chronic kidney disease

H Schiffl, SM Lang - International Urology and Nephrology, 2023‏ - Springer
Purpose The COVID-19 pandemic may have an impact on the long-term kidney function of
survivors. The clinical relevance is not clear. Methods This review summarises the currently …

Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

JS Gisby, NB Buang, A Papadaki, CL Clarke… - Nature …, 2022‏ - nature.com
Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here,
we perform longitudinal blood sampling of ESKD haemodialysis patients with COVID-19 …

Secondary immunodeficiency related to kidney disease (SIDKD)—definition, unmet need, and mechanisms

S Steiger, J Rossaint, A Zarbock… - Journal of the American …, 2022‏ - journals.lww.com
Kidney disease is a known risk factor for poor outcomes of COVID-19 and many other
serious infections. Conversely, infection is the second most common cause of death in …

[HTML][HTML] Outcomes following SARS-CoV-2 infection in individuals with and without solid organ transplantation—A Danish nationwide cohort study

M Overvad, A Koch, B Jespersen, F Gustafsson… - American Journal of …, 2022‏ - Elsevier
The risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,
hospitalization and death, and the effects of SARS-CoV-2 vaccines in solid organ transplant …

Disasters and kidney care: pitfalls and solutions

MS Sever, V Luyckx, M Tonelli, R Kazancioglu… - Nature Reviews …, 2023‏ - nature.com
Patients with kidney disease, especially those with kidney failure, are particularly
susceptible to the adverse effects of disasters because their survival depends on functional …

Asymptomatic hyperuricaemia in chronic kidney disease: mechanisms and clinical implications

HJ Anders, Q Li, S Steiger - Clinical kidney journal, 2023‏ - academic.oup.com
Asymptomatic hyperuricaemia (HU) is considered a pathogenic factor in multiple disease
contexts, but a causative role is only proven for the crystalline form of uric acid in gouty …

Paxlovid-tacrolimus drug–drug interaction in a 23-year-old female kidney transplant patient with COVID-19

N Berar Yanay, I Bogner, K Saker, E Tannous - Clinical drug investigation, 2022‏ - Springer
Kidney transplant patients are at a high risk for adverse severe acute respiratory syndrome
coronavirus 2 (SARSCOV-2) infection outcomes in terms of morbidity and mortality …

Molnupiravir when used alone seems to be safe and effective as outpatient COVID-19 therapy for hemodialyzed patients and kidney transplant recipients

P Poznański, H Augustyniak-Bartosik, A Magiera-Żak… - Viruses, 2022‏ - mdpi.com
Background: Molnupiravir demonstrated an in vitro antiviral activity against positive-sense
RNA viruses, including SARS-CoV-2. The study aimed to present the results of outpatient …

Immune responses to SARS-CoV-2 in dialysis and kidney transplantation

C Cantarelli, A Angeletti, L Perin, LS Russo… - Clinical Kidney …, 2022‏ - academic.oup.com
Despite progressive improvements in the management of patients with coronavirus disease
2019 (COVID-19), individuals with end-stage kidney disease (ESKD) are still at high risk of …