Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti‐rheumatic drugs for rheumatoid arthritis: a …

GS Hazlewood, C Barnabe… - Cochrane Database …, 2016‏ - cochranelibrary.com
Background Methotrexate is considered the preferred disease‐modifying anti‐rheumatic
drug (DMARD) for the treatment of rheumatoid arthritis, but controversy exists on the …

[HTML][HTML] Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated …

M Stevenson, R Archer, J Tosh… - Health technology …, 2016‏ - pmc.ncbi.nlm.nih.gov
OBJECTIVES Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with
increasing disability, reduced quality of life and substantial costs (as a result of both …

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease

E Biros, G Gäbel, CS Moran, C Schreurs… - …, 2015‏ - pmc.ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) and aortic occlusive disease (AOD) represent common
causes of morbidity and mortality in elderly populations which were previously believed to …

Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the …

MA D'Agostino, RJ Wakefield, H Berner-Hammer… - Annals of the rheumatic …, 2016‏ - Elsevier
Objectives To study the responsiveness of a combined power Doppler and greyscale
ultrasound (PDUS) score for assessing synovitis in biologic-naïve patients with rheumatoid …

Biologics or tofacitinib for rheumatoid arthritis in incomplete responders to methotrexate or other traditional disease‐modifying anti‐rheumatic drugs: a systematic …

JA Singh, A Hossain… - Cochrane Database …, 1996‏ - cochranelibrary.com
Background This is an update of the 2009 Cochrane overview and network meta‐analysis
(NMA) of biologics for rheumatoid arthritis (RA). Objectives To assess the benefits and …

Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis

M Cutolo, SG Nadler - Autoimmunity reviews, 2013‏ - Elsevier
Rheumatoid arthritis (RA) is a multifactorial and polygenic immune-mediated disease, the
pathogenesis of which involves different cell types. T and B lymphocytes, macrophages …

Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta‐analysis

JA Singh, A Hossain… - Cochrane Database …, 1996‏ - cochranelibrary.com
Background Biologic disease‐modifying anti‐rheumatic drugs (DMARDs: referred to as
biologics) are effective in treating rheumatoid arthritis (RA), however there are few head‐to …

Biologics or tofacitinib for people with rheumatoid arthritis naive to methotrexate: a systematic review and network meta‐analysis

JA Singh, A Hossain, AS Mudano… - Cochrane Database …, 1996‏ - cochranelibrary.com
Background Biologic disease‐modifying anti‐rheumatic drugs (biologics) are highly effective
in treating rheumatoid arthritis (RA), however there are few head‐to‐head biologic …

Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease‐modifying anti‐rheumatic drug (DMARD) failure: a Cochrane Systematic …

JA Singh, A Hossain… - Cochrane Database …, 1996‏ - cochranelibrary.com
Background We performed a systematic review, a standard meta‐analysis and network meta‐
analysis (NMA), which updates the 2009 Cochrane Overview,'Biologics for rheumatoid …

CTLA-4 blockade in the treatment of rheumatoid arthritis: an update

M Cutolo, A Sulli, S Paolino… - Expert Review of Clinical …, 2016‏ - Taylor & Francis
Rheumatoid arthritis (RA) is characterized by chronic joint inflammation as well as by extra-
articular involvement. The immunopathology of RA is polygenic and involves different cell …