The present and future role of microfluidics in biomedical research
Microfluidics, a technology characterized by the engineered manipulation of fluids at the
submillimetre scale, has shown considerable promise for improving diagnostics and biology …
submillimetre scale, has shown considerable promise for improving diagnostics and biology …
Micro total analysis systems for cell biology and biochemical assays
ML Kovarik, PC Gach, DM Ornoff, Y Wang… - Analytical …, 2012 - ACS Publications
Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and develo** innovative cell and …
biological questions, creating new biomedical reagents, and develo** innovative cell and …
Tumor spheroid-on-a-chip: a standardized microfluidic culture platform for investigating tumor angiogenesis
The field of microfluidics-based three-dimensional (3D) cell culture system is rapidly
progressing from academic proof-of-concept studies to valid solutions to real-world …
progressing from academic proof-of-concept studies to valid solutions to real-world …
User‐controlled 4D biomaterial degradation with substrate‐selective sortase transpeptidases for single‐cell biology
Stimuli‐responsive biomaterials show great promise for modeling disease dynamics ex vivo
with spatiotemporal control over the cellular microenvironment. However, harvesting cells …
with spatiotemporal control over the cellular microenvironment. However, harvesting cells …
Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs
Synthetic Notch (synNotch) receptors are genetically encoded, modular synthetic receptors
that enable mammalian cells to detect environmental signals and respond by activating user …
that enable mammalian cells to detect environmental signals and respond by activating user …
Open microfluidic capillary systems
Open microfluidic capillary systems are a rapidly evolving branch of microfluidics where
fluids are manipulated by capillary forces in channels lacking physical walls on all sides …
fluids are manipulated by capillary forces in channels lacking physical walls on all sides …
Suspended microfluidics
Although the field of microfluidics has made significant progress in bringing new tools to
address biological questions, the accessibility and adoption of microfluidics within the life …
address biological questions, the accessibility and adoption of microfluidics within the life …
Engineering organ-on-a-chip to accelerate translational research
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
Microfluidics within a well: an injection-molded plastic array 3D culture platform
Polydimethylsiloxane (PDMS) has been widely used in fabricating microfluidic devices for
prototy** and proof-of-concept experiments. Due to several material limitations, PDMS …
prototy** and proof-of-concept experiments. Due to several material limitations, PDMS …
[HTML][HTML] Engineered neural circuits for modeling brain physiology and neuropathology
The neural circuits of the central nervous system are the regulatory pathways for feeling,
motion control, learning, and memory, and their dysfunction is closely related to various …
motion control, learning, and memory, and their dysfunction is closely related to various …