Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of
years, it has helped humans fight diseases and protect life, health, and reproduction …

Ethnopharmacological relevance Aconitine, a C 19-norditerpenoid alkaloid, derives from
many medicinal plants such as Aconitum carmichaelii Debx.(Chinese: 乌头), Aconitum …

Terpenoids are a large class of natural secondary plant metabolites which are highly diverse
in structure, formed from isoprene units (C-5), associated with a wide range of biological …

Aconitine (AC) is well‐known as the main toxic ingredient and active compound of Aconitum
species, of which several aconites are essential herbal medicines of Traditional Chinese …

Aconitine is a diterpenoid alkaloid, which mainly exists in the plants of Aconitum. In the last
decade, a plethora of studies on the pharmacological activities of aconitine has been …

Non-alcoholic fatty liver disease (NAFLD) has become one of the most common chronic liver
diseases worldwide, and its prevalence is still growing rapidly. However, the efficient …

Background Aconitine-induced cardiotoxicity limits the clinical treatment of cardiotonic,
cancers and immune-related diseases. Ginsenoside Rb1 (Rb1) is an active ingredient of …

Aims: Sweroside, a secoiridoid glucoside extracted from Swertia pseudochinensis Hara, is
reported to possess antioxidant and anti-inflammatory activities. However, whether …

Abstract DNA methyltransferase 1 (DNMT1) shows close link with heart disease. This study
aimed to define the role DNMT1 plays in heart failure and determine the underlying …

Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but
also contributes to the high morbidity and mortality rates of cardiovascular diseases …