Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …

The mechanical properties of cells and tissues help determine their architecture,
composition and function. Alterations to these properties are associated with many diseases …

Background: Tumorigenesis is attributed to the interactions of cancer cells with the tumor
microenvironment through both biochemical cues and physical stimuli. Increased matrix …

The mechanical properties of cells strongly regulate many physiological and pathological
processes. For example, in cancer, invasive and metastatic tumor cells have often been …

The mechanical properties of cancer cells and their microenvironment contribute to breast
cancer progression. While mechanosensing has been extensively studied using 2D …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

Living cells are constantly exchanging momentum with their surroundings. So far, there is no
consensus regarding how cells respond to such external stimuli, although it reveals much …

Tissue morphology and mechanics are crucial to the regulation of organ function.
Investigating the exceptionally complex tissue of the brain at the sub-micron scale is …

Extracellular matrix (ECM), as a dynamic component of the tissue, influences cell behavior
and plays an important role in cell mechanics and tissue homeostasis. Reciprocally, this …

The determination of mechanical properties of living cells as an indicator of cancer
progression has become possible with the development of local measurement techniques …