Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has
accumulated 15 years of clinical, neuroimaging, cognitive, biofluid biomarker and genetic …

The burden of dementia continues to increase as the population ages, with no disease-
modifying treatments available. However, dementia risk appears to be decreasing, and …

Background and objectives The present study aimed to investigate the relation between
anemia and hemoglobin (Hgb) concentration, physical performance, and cognitive function …

The prevalence of dementia has been widely reported, and its potential risk and protective
factors are well-characterized. However, there is a scarcity of related information regarding …

Cognitive reserve is present in Alzheimer's disease (AD) seniors with high education
attainment making them clinically resilient to extended brain neuropathology and …

Over 55 million people globally are living with dementia and, by 2050, this number is
projected to increase to 131 million. This poses immeasurable challenges for patients and …

The study of the hippocampus across the healthy adult lifespan has rendered inconsistent
findings. While volumetric measurements have often been a popular technique for analysis …

The posterior cingulate cortex, a key hub of the default mode network, underlies
autobiographical memory retrieval and displays hypometabolic changes early in Alzheimer …

Research suggests that social, physical, and cognitively challenging activities during
lifetime, could mitigate the negative effects of aging on cognitive function. This effect is …