Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

The study of transient chemical phenomena by conventional NMR has proved elusive,
particularly for non-1H nuclei. For 13C, hyperpolarization using the dynamic nuclear …

Saliva is a readily accessible and informative biofluid, making it ideal for the early detection
of a wide range of diseases including cardiovascular, renal, and autoimmune diseases, viral …

Biochemical analyses reveal that plasma contains over 600 structural forms of lipid
molecules. This review summarizes known correlations between levels of lipid moieties and …

Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …

Prostate cancer (PCa) is the most common malignancy in men worldwide, leading to
substantial morbidity and mortality. At present, imaging of PCa has become increasingly …

Phospholipids represent a crucial component for the structure of cell membranes.
Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise …

Following the impetus of early clinical and experimental investigations, in vivo and in vitro
MRS studies of tumours pointed in the eighties to the possible significance of signals arising …

Magnetic resonance spectroscopy (MRS) affords a noninvasive window on in vivo brain
chemistry and, as such, provides a unique opportunity to gain insight into the biochemical …

The therapeutic efficacy of imatinib mesylate (Gleevec) is based on its specific inhibition of
the BCR-ABL oncogene protein, a widely expressed tyrosine kinase in chronic …