We have developed a general profile for the proteins of the TetR family of repressors. The
stretch that best defines the profile of this family is made up of 47 amino acid residues that …

Lipocalins are remarkably diverse at the sequence level yet have highly conserved
structures. Most lipocalins share three characteristic conserved sequence motifs–the kernel …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

InterProScan is a tool that scans given protein sequences against the protein signatures of
the InterPro member databases, currently–PROSITE, PRINTS, Pfam, ProDom and SMART …

Reference datasets are critical in computational biology. They help define canonical
biological features and are essential for benchmarking studies. Here, we describe a …

Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …

On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein
Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Signature databases are vital tools for identifying distant relationships in novel sequences
and hence for inferring protein function. InterPro is an integrated documentation resource for …

The genome sequence of an organism is an information resource unlike any that biologists
have previously had access to. But the value of the genome is only as good as its …