Nrf2/ARE pathway modulation by dietary energy regulation in neurological disorders

AR Vasconcelos, NB Dos Santos, C Scavone… - Frontiers in …, 2019‏ - frontiersin.org
Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates the expression of an array of
enzymes with important detoxifying and antioxidant functions. Current findings support the …

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom

P Stenvinkel, J Painer, M Kuro-o, M Lanaspa… - Nature Reviews …, 2018‏ - nature.com
Many of the> 2 million animal species that inhabit Earth have developed survival
mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration …

Synergistic antioxidant effects of resveratrol and curcumin against fipronil-triggered oxidative damage in male albino rats

G AlBasher, MM Abdel-Daim, R Almeer… - … Science and Pollution …, 2020‏ - Springer
Fipronil (FPN), a phenylpyrazole insecticide, has been receiving increased attention owing
to its toxicity, which is largely mediated through its effects on antioxidant systems. The …

Acute aflatoxin B1-induced hepatic and cardiac oxidative damage in rats: Ameliorative effects of morin

AE Altyar, OA Kensara, AA Sayed, L Aleya… - Heliyon, 2023‏ - cell.com
Aflatoxins (AFs) are secondary metabolites produced by the fungus Aspergillus flavus, of
which Aflatoxin-B1 (AFB1) appears to be the most cancerogenic and of the highest toxicity …

[HTML][HTML] Liver injury induced by carbon tetrachloride in mice is prevented by the antioxidant capacity of Anji white tea polyphenols

R Wang, Z Yang, J Zhang, J Mu, X Zhou, X Zhao - Antioxidants, 2019‏ - mdpi.com
Anji white tea is a unique variety of green tea that is rich in polyphenols. In this study, the
effect of Anji white tea polyphenols (AJWTP) on the prevention of carbon tetrachloride …

Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats

MM Abdel-Daim, HM Shaheen, AI Abushouk… - … Science and Pollution …, 2018‏ - Springer
Fipronil (FPN) is a phenylpyrazole insecticide, widely used for agricultural and veterinary
activities. Early reports indicated that FIP organ toxicity is primarily mediated by the induction …

Fasting ameliorates oxidative stress: A review of physiological strategies across life history events in wild vertebrates

DC Ensminger, A Salvador-Pascual, BG Arango… - … and Physiology Part A …, 2021‏ - Elsevier
Fasting is a component of many species' life history due to environmental factors or
behavioral patterns that limit access to food. Despite metabolic and physiological challenges …

[HTML][HTML] Influence of long-term fasting on blood redox status in humans

F Wilhelmi de Toledo, F Grundler, N Goutzourelas… - Antioxidants, 2020‏ - mdpi.com
Fasting is increasingly practiced to improve health and general well-being, as well as for its
cytoprotective effects. Changes in blood redox status, linked to the development of a variety …

Natural tolerance to ischemia and hypoxemia in diving mammals: a review

KN Allen, JP Vázquez-Medina - Frontiers in physiology, 2019‏ - frontiersin.org
Reperfusion injury follows ischemia/reperfusion events occurring during myocardial
infarction, stroke, embolism, and other peripheral vascular diseases. Decreased blood flow …

Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals

KN Allen, JM Torres-Velarde, JM Vazquez… - BMC biology, 2024‏ - Springer
Background Elephant seals exhibit extreme hypoxemic tolerance derived from repetitive
hypoxia/reoxygenation episodes they experience during diving bouts. Real-time …