Ancient DNA damage

J Dabney, M Meyer, S Pääbo - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Under favorable conditions DNA can survive for thousands of years in the remains of dead
organisms. The DNA extracted from such remains is invariably degraded to a small average …

Genetic analyses from ancient DNA

S Pääbo, H Poinar, D Serre… - Annu. Rev …, 2004 - annualreviews.org
▪ Abstract About 20 years ago, DNA sequences were separately described from the quagga
(a type of zebra) and an ancient Egyptian individual. What made these DNA sequences …

Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans

M Raghavan, P Skoglund, KE Graf, M Metspalu… - Nature, 2014 - nature.com
The origins of the First Americans remain contentious. Although Native Americans seem to
be genetically most closely related to east Asians,,, there is no consensus with regard to …

The use and domestication of Theobroma cacao during the mid-Holocene in the upper Amazon

S Zarrillo, N Gaikwad, C Lanaud, T Powis… - Nature ecology & …, 2018 - nature.com
Cacao (Theobroma cacao L.) is an important economic crop, yet studies of its domestication
history and early uses are limited. Traditionally, cacao is thought to have been first …

Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal

P Skoglund, BH Northoff, MV Shunkov… - Proceedings of the …, 2014 - National Acad Sciences
One of the main impediments for obtaining DNA sequences from ancient human skeletons is
the presence of contaminating modern human DNA molecules in many fossil samples and …

Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers

P Skoglund, H Malmström, A Omrak, M Raghavan… - Science, 2014 - science.org
Prehistoric population structure associated with the transition to an agricultural lifestyle in
Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone …

Diverse plant and animal genetic records from Holocene and Pleistocene sediments

E Willerslev, AJ Hansen, J Binladen, TB Brand… - Science, 2003 - science.org
Genetic analyses of permafrost and temperate sediments reveal that plant and animal DNA
may be preserved for long periods, even in the absence of obvious macrofossils. In Siberia …

Ancient dna

E Willerslev, A Cooper - Proceedings of the Royal …, 2005 - royalsocietypublishing.org
In the past two decades, ancient DNA research has progressed from the retrieval of small
fragments of mitochondrial DNA from a few late Holocene specimens, to large-scale studies …

DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA

M Hofreiter, V Jaenicke, D Serre… - Nucleic acids …, 2001 - academic.oup.com
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and
teeth that vary in age between 25 000 and over 50 000 years carry C→ T and G→ A …

Forensic implications of genetic analyses from degraded DNA—a review

R Alaeddini, SJ Walsh, A Abbas - Forensic science international: genetics, 2010 - Elsevier
Forensic DNA identification techniques are principally based on determination of the size or
sequence of desired PCR products. The fragmentation of DNA templates or the structural …