[HTML][HTML] Vero cell upstream bioprocess development for the production of viral vectors and vaccines
The Vero cell line is considered the most used continuous cell line for the production of viral
vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the …
vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the …
Phylogenomic analyses provide insights into primate evolution
Comparative analysis of primate genomes within a phylogenetic context is essential for
understanding the evolution of human genetic architecture and primate diversity. We present …
understanding the evolution of human genetic architecture and primate diversity. We present …
From evolution to function: Two sides of the same CENP-B coin?
The centromere is the nucleoproteic chromosomal structure necessary for accurate
chromosome segregation during cell division. One of the earliest centromeric proteins to be …
chromosome segregation during cell division. One of the earliest centromeric proteins to be …
Genomic flatlining in the endangered island fox
Genetic studies of rare and endangered species often focus on defining and preserving
genetically distinct populations, especially those having unique adaptations [1, 2]. Much less …
genetically distinct populations, especially those having unique adaptations [1, 2]. Much less …
Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out …
have changed research direction to understand better how the virus works and to find out …
Non-B-form DNA is enriched at centromeres
Animal and plant centromeres are embedded in repetitive “satellite” DNA, but are thought to
be epigenetically specified. To define genetic characteristics of centromeres, we surveyed …
be epigenetically specified. To define genetic characteristics of centromeres, we surveyed …
The comparative genomics and complex population history of Papio baboons
Recent studies suggest that closely related species can accumulate substantial genetic and
phenotypic differences despite ongoing gene flow, thus challenging traditional ideas …
phenotypic differences despite ongoing gene flow, thus challenging traditional ideas …
The impact of purifying and background selection on the inference of population history: problems and prospects
Current procedures for inferring population history generally assume complete neutrality—
that is, they neglect both direct selection and the effects of selection on linked sites. We here …
that is, they neglect both direct selection and the effects of selection on linked sites. We here …
Population dynamics and genetic connectivity in recent chimpanzee history
Knowledge on the population history of endangered species is critical for conservation, but
whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we …
whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we …
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations
Vervet monkeys are among the most widely distributed nonhuman primates, show
considerable phenotypic diversity, and have long been an important biomedical model for a …
considerable phenotypic diversity, and have long been an important biomedical model for a …