Photodynamic therapy (PDT) has been a preferred clinical technology for treating superficial
tumors due to its advantages of high selectivity, non-invasiveness and negligible drug …

Fluorophores with aggregation-induced emission (AIE) are characterized by many
advantageous features for biomedical applications, including excellent photostability and …

A unique type of pH/H2 O2 dual-responsive intelligent nanoscale delivery system based on
albumin-coated MnO2 is presented, which is capable of modulating the tumor …

Hypoxia not only promotes tumor metastasis but also strengthens tumor resistance to
therapies that demand the involvement of oxygen, such as radiation therapy and …

Photodynamic therapy (PDT), which utilizes reactive oxygen species to kill cancer cells, has
found wide applications in cancer treatment. However, the hypoxic nature of most solid …

Multifunctional nanoplatforms for imaging‐guided synergistic antitumor treatment are highly
desirable in biomedical applications. However, anticancer treatment is largely affected by …

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to
cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor …

Background & Aims Most pancreatic ductal adenocarcinomas (PDACs) express an activated
form of KRAS, become hypoxic and dysplastic, and are refractory to chemo and radiation …

Tumor hypoxia is known to be one of critical factors that aggravate the tumor resistance to
photodynamic therapy (PDT) in which oxygen is essential for tumor destruction. Herein …

Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is estimated to become the second
leading cause of cancer-related deaths by 2030 with mortality rates of up to 93%. Standard …