The kainic acid model of temporal lobe epilepsy

M Lévesque, M Avoli - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …

The kainic acid models of temporal lobe epilepsy

E Rusina, C Bernard, A Williamson - Eneuro, 2021 - eneuro.org
Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …

Epilepsy in children

R Guerrini - The Lancet, 2006 - thelancet.com
Summary 10· 5 million children worldwide are estimated to have active epilepsy. Over the
past 15 years, syndrome-oriented clinical and EEG diagnosis, and better aetiological …

Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications

DP Soares, M Law - Clinical radiology, 2009 - Elsevier
Magnetic resonance imaging (MRI) provides anatomic images and morphometric
characterization of disease, whereas magnetic resonance spectroscopy (MRS) provides …

Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging

C Watson, F Andermann, P Gloor, M Jones-Gotman… - Neurology, 1992 - AAN Enterprises
Both the amygdala and the hippocampus are involved in the pathogenesis of a number of
neurologic conditions, including temporal lobe epilepsy, postanoxic amnesia, and …

Characteristics of medial temporal lobe epilepsy: II. Interictal and ictal scalp electroencephalography, neuropsychological testing, neuroimaging, surgical results, and …

PD Williamson, JA French, VM Thadani… - Annals of Neurology …, 1993 - Wiley Online Library
Sixty‐seven patients with temporal lobe epilepsy without circumscribed, potentially
epileptogenic lesions, who were studied with intracranial electrodes and who became …

Hippocampal sclerosis—origins and imaging

K Malmgren, M Thom - Epilepsia, 2012 - Wiley Online Library
The association between hippocampal sclerosis (HS) and epilepsy has been known for
almost two centuries. For many years, HS was studied in postmortem series; however, since …

MRI volumetric measurement of amygdala and hippocampus in temporal lobe epilepsy

F Cendes, F Andermann, P Gloor, A Evans… - Neurology, 1993 - AAN Enterprises
We performed MRI volumetric measurements of the amygdala (AM), the hippocampal
formation (HF), and the anterior temporal lobe in a group of 30 patients with intractable …

The relative contributions of MRI, SPECT, and PET imaging in epilepsy

SS Spencer - Epilepsia, 1994 - Wiley Online Library
Functional and structural neuroimaging techniques are increasingly indispensable in the
evaluation of epileptic patients for localization of the epileptic area as well as for …

MRI-negative PET-positive temporal lobe epilepsy: a distinct surgically remediable syndrome

RP Carne, TJ O'brien, CJ Kilpatrick, LR MacGregor… - Brain, 2004 - academic.oup.com
Most patients with non-lesional temporal lobe epilepsy (NLTLE) will have the findings of
hippocampal sclerosis (HS) on a high resolution MRI. However, a significant minority of …