This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Optical sensing of specific molecular targets and pathways deep inside living mice has
become possible as a result of a number of advances. These include design of …

The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Multiple biomedical imaging techniques are used in all phases of cancer management.
Imaging forms an essential part of cancer clinical protocols and is able to furnish …

We review the current state-of-the-art of diffuse optical imaging, which is an emerging
technique for functional imaging of biological tissue. It involves generating images using …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

We present quantitative optical images of human breast in vivo. The images were obtained
by using near-infrared diffuse optical tomography (DOT) after the administration of …

Diffuse optical imaging (DOI) may be a beneficial diagnostic method for women with
mammographically dense breast tissue. In order to evaluate the utility of DOI, we are …

Infrared (IR) imaging in medicine has been used in the past but without the advantage of
twenty-firstcentury technology. In 1994, under the Department of Defense (DOD) grants …

We demonstrate that synthetic soft materials can extend the utility of natural vesicles, from
predominantly hydrophilic reservoirs to functional colloidal carriers that facilitate the …