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Obesity, inflammation, and immune system in osteoarthritis
Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …
Obese visceral fat tissue inflammation: from protective to detrimental?
H Kolb - BMC medicine, 2022 - Springer
Obesity usually is accompanied by inflammation of fat tissue, with a prominent role of
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …
Metabolic inflammation and insulin resistance in obesity
H Wu, CM Ballantyne - Circulation research, 2020 - ahajournals.org
Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
Obesity and diabetes as high‐risk factors for severe coronavirus disease 2019 (Covid‐19)
Y Zhou, J Chi, W Lv, Y Wang - Diabetes/metabolism research …, 2021 - Wiley Online Library
The outbreak of the coronavirus disease 2019 (Covid‐19) has become an evolving
worldwide health crisis. With the rising prevalence of obesity and diabetes has come an …
worldwide health crisis. With the rising prevalence of obesity and diabetes has come an …
Adipose tissue inflammation and metabolic dysfunction in obesity
Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …
Adipokine dysregulation and adipose tissue inflammation in human obesity
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
[HTML][HTML] Plasticity of epididymal adipose tissue in response to diet-induced obesity at single-nucleus resolution
AK Sárvári, EL Van Hauwaert, LK Markussen… - Cell metabolism, 2021 - cell.com
Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …
Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - pmc.ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
[HTML][HTML] The mechanism behind influenza virus cytokine storm
Y Gu, X Zuo, S Zhang, Z Ouyang, S Jiang, F Wang… - Viruses, 2021 - mdpi.com
Influenza viruses are still a serious threat to human health. Cytokines are essential for cell-to-
cell communication and viral clearance in the immune system, but excessive cytokines can …
cell communication and viral clearance in the immune system, but excessive cytokines can …
Obesity-associated microbiomes instigate visceral adipose tissue inflammation by recruitment of distinct neutrophils
D Shantaram, R Hoyd, AM Blaszczak, L Antwi… - Nature …, 2024 - nature.com
Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders.
Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains …
Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains …