Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Objective: To evaluate the association between migraine without aura (MO) and migraine
with aura (MA) and 3 types of structural brain abnormalities detected by MRI: white matter …

MR-based brain imaging technologies provide a suite of functional and structural metrics
that can be used to test hypotheses about the CNS mechanisms underlying pain perception …

This review and meta-analysis aims at summarizing and integrating the human
neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original …

Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …

Objective: The periaqueductal gray matter (PAG), a known modulator of somatic pain
transmission, shows evidence of interictal functional and structural abnormalities in …

Previous studies have suggested that migraine is a risk factor for brain lesions, but
methodological issues hampered drawing definite conclusions. Therefore, we initiated the …

Objective.—We investigated in a sham‐controlled trial the analgesic effects of a 4‐week
treatment of transcranial direct current stimulation (tDCS) over the primary motor cortex in …

Several lines of evidence suggest a major role of the trigeminovascular system in the
pathogenesis of migraine. Using functional magnetic resonance imaging (fMRI), we …