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A review on the role of cyclin dependent kinases in cancers
S Ghafouri-Fard, T Khoshbakht, BM Hussen… - Cancer Cell …, 2022 - Springer
The Cyclin-dependent kinase (CDK) class of serine/threonine kinases has crucial roles in
the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers …
the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers …
[HTML][HTML] Using ncRNAs as tools in Cancer diagnosis and treatment—the way towards personalized medicine to improve patients' health
R Piergentili, G Basile, C Nocella, R Carnevale… - International journal of …, 2022 - mdpi.com
Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …
years has the complexity of the transcriptome started to be elucidated. However, its …
Cancer hallmarks and MicroRNAs: the therapeutic connection
K Van Roosbroeck, GA Calin - Advances in cancer research, 2017 - Elsevier
Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …
Roles of the canonical myomiRs miR-1,-133 and-206 in cell development and disease
KR Mitchelson, WY Qin - World journal of biological chemistry, 2015 - pmc.ncbi.nlm.nih.gov
MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …
providing subtle combinational regulation of cellular pathways, often by regulating …
Regulation of cancer metastasis by microRNAs
SH Chan, LH Wang - Journal of Biomedical Science, 2015 - Springer
MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that have been
found highly conserved among species. MiRNAs are able to negatively regulate gene …
found highly conserved among species. MiRNAs are able to negatively regulate gene …
Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation
Hsa-miRNA-206 (miR-206), highly expressed in skeletal muscle, has recently been
discovered to have anticancer properties in different tissues. However, the role of miR-206 …
discovered to have anticancer properties in different tissues. However, the role of miR-206 …
[HTML][HTML] MiR-206 inhibits epithelial ovarian cancer cells growth and invasion via blocking c-Met/AKT/mTOR signaling pathway
C Dai, Y **e, X Zhuang, Z Yuan - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background MicroRNAs play important roles in the pathogenesis of various kinds of tumors.
However, there are few studies on the expression profile and function of miRNAs in …
However, there are few studies on the expression profile and function of miRNAs in …
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206
SH Wang, WJ Zhang, XC Wu, MD Zhang… - …, 2016 - pmc.ncbi.nlm.nih.gov
Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(Malat1) functions as an oncogene in many types of human cancer. In this study, we show …
(Malat1) functions as an oncogene in many types of human cancer. In this study, we show …
Regulation of the cell cycle by ncRNAs affects the efficiency of CDK4/6 inhibition
Q Hu, T Huang - International Journal of Molecular Sciences, 2023 - mdpi.com
Cyclin-dependent kinases (CDKs) regulate cell division at multiple levels. Aberrant
proliferation induced by abnormal cell cycle is a hallmark of cancer. Over the past few …
proliferation induced by abnormal cell cycle is a hallmark of cancer. Over the past few …
An update on the implications of cyclin D1 in melanomas
L González‐Ruiz, MÁ González‐Moles… - Pigment cell & …, 2020 - Wiley Online Library
Cyclin D1 is a protein encoded by the CCND1 gene, located on 11q13 chromosome, which
is a key component of the physiological regulation of the cell cycle. CCND1/cyclin D1 is …
is a key component of the physiological regulation of the cell cycle. CCND1/cyclin D1 is …