About 280 million people suffer from depression as the most common neurological disorder
and the most common cause of death worldwide. Exercise with serotonin released in the …

Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

Background Neuroinflammation is a crucial factor in the development of secondary brain
injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers …

Exercise has multiple beneficial effects on health including decreasing the risk of
neurodegenerative diseases. Such effects are thought to be mediated (at least in part) by …

Alzheimer's disease (AD) is a common cause of dementia characterized by
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …

Three decades of animal studies have reproducibly shown that hypothermia is profoundly
cerebroprotective during or after a central nervous system (CNS) insult. The success of …

Depression is the most prevalent psychiatric disorder experienced by the world's population.
Mechanisms associated with depression-like behavior have not been fully investigated …

Cerebral ischemia contributes to significant disabilities worldwide, impairing cognitive
function and motor coordination in affected individuals. Stroke has severe …

The complexity of depression presents a significant challenge to traditional treatment
methods, such as medication and psychotherapy. Recent studies have shown that exercise …

Introduction Post-stroke depression (PSD), one of the most common complications following
stroke, affects approximately one-third of stroke patients and is significantly associated with …