The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

The incidence of liver diseases is high worldwide. Many factors can cause liver fibrosis,
which in turn can lead to liver cirrhosis and even liver cancer. Due to the shortage of donor …

Mimicking nativelike metabolic zonation is indispensable to develop an efficient bioartificial
liver model, as it facilitates physiological cues, hepatocyte polarity, and phenotypic functions …

Diabetes is an emerging global epidemic that affects more that 285 million people
worldwide. Engineering of endocrine pancreas tissue holds great promise for the future of …

Tissue-engineered is an effective method for repairing critical-size bone defects. The
application of bioactive scaffold provides artificial matrix and suitable microenvironment for …

Allogeneic transplant organs are potentially highly immunogenic. The endothelial cells
(ECs) located within the vascular system serve as the primary interface between the …

The field of bone tissue engineering (BTE) has witnessed a revolutionary breakthrough with
the advent of three-dimensional (3D) bioprinting technology, which is considered an ideal …

Currently, Type 1 diabetes (T1D) can be treated through implantation of allogenic islets,
which replenish the beta cell population, however this method requires an extensive post …

Background: Previous reports showed that mouse embryonic fibroblasts (MEFs) could
support pluripotent stem cell self-renewal and maintain their pluripotency. The goal of this …

Diabetes has become an increasingly prominent global issue afflicting 10% of world's
population where type 2 diabetes (T2D) comprises the majority of those diagnosed. T2D …