The role of oxidative stress in the pathophysiology of gestational diabetes mellitus

M Lappas, U Hiden, G Desoye, J Froehlich… - Antioxidants & redox …, 2011 - liebertpub.com
Normal human pregnancy is considered a state of enhanced oxidative stress. In pregnancy,
it plays important roles in embryo development, implantation, placental development and …

Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species

J Ramalho-Santos, S Amaral… - Current diabetes …, 2008 - ingentaconnect.com
Diabetes Mellitus (DM), a state of chronic hyperglycemia, is a major cause of serious micro
and macrovascular diseases, affecting, therefore, nearly every system in the body. Growing …

Streptozotocin‐induced diabetes models: Pathophysiological mechanisms and fetal outcomes

DC Damasceno, AO Netto, IL Iessi… - BioMed research …, 2014 - Wiley Online Library
Glucose homeostasis is controlled by endocrine pancreatic cells, and any pancreatic
disturbance can result in diabetes. Because 8% to 12% of diabetic pregnant women present …

Oxidative stress in streptozotocin-induced diabetic rats: effects of garlic oil and melatonin

MM Anwar, ARMA Meki - Comparative Biochemistry and Physiology Part A …, 2003 - Elsevier
In the present study, oxidative stress in diabetic model and the effect of garlic oil or
melatonin treatment were examined. Streptozotocin (60 mg/kg body weight, ip)-induced …

[HTML][HTML] The role of xanthine oxidase in pregnancy complications: a systematic review

L Annesi, G Tossetta, C Borghi, F Piani - Antioxidants, 2024 - mdpi.com
Xanthine oxidoreductase (XOR) is an enzyme involved in the oxidation of hypoxanthine and
xanthine to uric acid. XOR has two isoforms: xanthine dehydrogenase and xanthine oxidase …

Oxidative stress in development: nature or nurture?

PA Dennery - Free Radical Biology and Medicine, 2010 - Elsevier
An unavoidable consequence of aerobic respiration is the generation of reactive oxygen
species (ROS). These may negatively impact development. Nevertheless, a certain amount …

Quercetin allievates oxidative stress in streptozotocin‐induced diabetic rats

T Mahesh, VP Menon - Phytotherapy Research: An …, 2004 - Wiley Online Library
Diabetes mellitus is found in almost all populations and is emerging as a growing problem in
develo** countries. A large number of studies are in progress to find natural sources …

Animal models in diabetes and pregnancy

A Jawerbaum, V White - Endocrine Reviews, 2010 - academic.oup.com
The worldwide increase in the incidence of diabetes, the increase in type 2 diabetes in
women at reproductive ages, and the cross-generation of the intrauterine programming of …

Protective effects of moderate exercise with dietary vitamin C and E on blood antioxidative defense mechanism in rats with streptozotocin-induced diabetes

M Naziroğlu, PJ Butterworth - Canadian journal of applied …, 2005 - cdnsciencepub.com
Daily moderate exercise and supplementation of vitamins C and E (VCE) can be beneficial
in diabetes by ameliorating the effects of free radical production. The present study sought to …

Diabetic-associated stillbirth: incidence, pathophysiology, and prevention

DJ Dudley - Clinics in perinatology, 2007 - Elsevier
All forms of diabetes during pregnancy are associated with an increased risk for stillbirth,
defined as fetal death at greater than 20 weeks. The incidence of stillbirth in women who …