Comparative analyses of gene co-expression networks: Implementations and applications in the study of evolution

K Ovens, BF Eames, I McQuillan - Frontiers in Genetics, 2021 - frontiersin.org
Similarities and differences in the associations of biological entities among species can
provide us with a better understanding of evolutionary relationships. Often the evolution of …

[HTML][HTML] Network-based approaches for modeling disease regulation and progression

G Galindez, S Sadegh, J Baumbach… - Computational and …, 2023 - Elsevier
Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …

Gene co-expression analysis for functional classification and gene–disease predictions

S Van Dam, U Vosa, A van der Graaf… - Briefings in …, 2018 - academic.oup.com
Gene co-expression networks can be used to associate genes of unknown function with
biological processes, to prioritize candidate disease genes or to discern transcriptional …

CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses

PST Russo, GR Ferreira, LE Cardozo, MC Bürger… - BMC …, 2018 - Springer
Background The analysis of modular gene co-expression networks is a well-established
method commonly used for discovering the systems-level functionality of genes. In addition …

Natural history–guided omics reveals plant defensive chemistry against leafhopper pests

Y Bai, C Yang, R Halitschke, C Paetz, D Kessler… - Science, 2022 - science.org
Although much is known about plant traits that function in nonhost resistance against
pathogens, little is known about nonhost resistance against herbivores, despite its …

DGCA: a comprehensive R package for differential gene correlation analysis

AT McKenzie, I Katsyv, WM Song, M Wang… - BMC systems …, 2016 - Springer
Background Dissecting the regulatory relationships between genes is a critical step towards
building accurate predictive models of biological systems. A powerful approach towards this …

Improved biomarker discovery through a plot twist in transcriptomic data analysis

N Sánchez-Baizán, L Ribas, F Piferrer - BMC biology, 2022 - Springer
Background Transcriptomic analysis is crucial for understanding the functional elements of
the genome, with the classic method consisting of screening transcriptomics datasets for …

Dissection of regulatory networks that are altered in disease via differential co-expression

D Amar, H Safer, R Shamir - PLoS computational biology, 2013 - journals.plos.org
Comparing the gene-expression profiles of sick and healthy individuals can help in
understanding disease. Such differential expression analysis is a well-established way to …

[HTML][HTML] DiffCorr: an R package to analyze and visualize differential correlations in biological networks

A Fukushima - Gene, 2013 - Elsevier
Large-scale “omics” data, such as microarrays, can be used to infer underlying cellular
regulatory networks in organisms, enabling us to better understand the molecular basis of …

Host transcriptional response to influenza and other acute respiratory viral infections–a prospective cohort study

Y Zhai, LM Franco, RL Atmar, JM Quarles… - PLoS …, 2015 - journals.plos.org
To better understand the systemic response to naturally acquired acute respiratory viral
infections, we prospectively enrolled 1610 healthy adults in 2009 and 2010. Of these, 142 …