Synthetic fluorescent probes for studying copper in biological systems

JA Cotruvo Jr, AT Aron, KM Ramos-Torres… - Chemical Society …, 2015 - pubs.rsc.org
The potent redox activity of copper is required for sustaining life. Mismanagement of its
cellular pools, however, can result in oxidative stress and damage connected to aging …

Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols

LM Hyman, KJ Franz - Coordination chemistry reviews, 2012 - Elsevier
Oxidative stress is a common feature shared by many diseases, including
neurodegenerative diseases. Factors that contribute to cellular oxidative stress include …

A highly selective turn-on fluorescent probe for iron (II) to visualize labile iron in living cells

T Hirayama, K Okuda, H Nagasawa - Chemical science, 2013 - pubs.rsc.org
Although labile iron plays critical roles in diverse biological processes in living cells, the
physiological and pathophysiological functions of iron have not been sufficiently explored …

Analytical methods for imaging metals in biology: from transition metal metabolism to transition metal signaling

CM Ackerman, S Lee, CJ Chang - Analytical chemistry, 2017 - ACS Publications
Metal elements represent some of the most fundamental chemical building blocks of life and
are required to sustain the growth, development, and sustenance of all living organisms and …

NIR- and FRET-Based Sensing of Cu2+ and S2- in Physiological Conditions and in Live Cells

C Kar, MD Adhikari, A Ramesh, G Das - Inorganic Chemistry, 2013 - ACS Publications
We have synthesized a new indole functionalized rhodamine derivative L 1 which
specifically binds to Cu2+ in the presence of large excess of other competing ions with …

Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model

T Hirayama, GC Van de Bittner… - Proceedings of the …, 2012 - National Acad Sciences
Copper is an essential metal nutrient that is tightly regulated in the body because loss of its
homeostasis is connected to severe diseases such as Menkes and Wilson diseases …

Visible–Near‐Infrared and Fluorescent Copper Sensors Based on Julolidine Conjugates: Selective Detection and Fluorescence Imaging in Living Cells

D Maity, AK Manna, D Karthigeyan… - … A European Journal, 2011 - Wiley Online Library
We present novel Schiff base ligands julolidine–carbonohydrazone 1 and julolidine–
thiocarbonohydrazone 2 for selective detection of Cu2+ in aqueous medium. The planar …

Advances in the selection of functional monomers for molecularly imprinted polymers: A review

J Niu, M Du, W Wu, J Yang… - Journal of Separation …, 2024 - Wiley Online Library
Molecularly imprinted polymers, a type of special polymer materials, are widely used in
biosensing and other fields due to their ability to specifically recognize target molecules …

Reactive Probes for Ratiometric Detection of Co2+ and Cu+ Based on Excited-State Intramolecular Proton Transfer Mechanism

D Maity, V Kumar, T Govindaraju - Organic letters, 2012 - ACS Publications
An excited-state intramolecular proton transfer (ESIPT) mechanism based two reactive
probes HBTCo and HBTCu is reported for the selective detection of Co2+ and Cu+ …

Synthetic fluorescent probes to map metallostasis and intracellular fate of zinc and copper

GT Sfrazzetto, C Satriano, GA Tomaselli… - Coordination Chemistry …, 2016 - Elsevier
The intracellular tracking of zinc and copper, metals essential for life, is nowadays pivotal to
unravel the complex mechanism that involves the physiological or pathological role of such …