Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

Basic concepts and recent advances in nanogels as carriers for medical applications

I Neamtu, AG Rusu, A Diaconu, LE Nita, AP Chiriac - Drug delivery, 2017 - Taylor & Francis
Nanogels in biomedical field are promising and innovative materials as dispersions of
hydrogel nanoparticles based on crosslinked polymeric networks that have been called as …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in develo** polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Progress of drug-loaded polymeric micelles into clinical studies

H Cabral, K Kataoka - Journal of Controlled Release, 2014 - Elsevier
Targeting tumors with long-circulating nano-scaled carriers is a promising strategy for
systemic cancer treatment. Compared with free small therapeutic agents, nanocarriers can …

Advanced materials and processing for drug delivery: the past and the future

Y Zhang, HF Chan, KW Leong - Advanced drug delivery reviews, 2013 - Elsevier
Design and synthesis of efficient drug delivery systems are of vital importance for medicine
and healthcare. Materials innovation and nanotechnology have synergistically fueled the …

Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance

Z Ge, S Liu - Chemical Society Reviews, 2013 - pubs.rsc.org
Self-assembled nanostructures of amphiphilic and double hydrophilic block copolymers
have been increasingly utilized as potent polymeric nanocarriers of therapeutic drugs …

Block copolymer micelles for drug delivery: design, characterization and biological significance

K Kataoka, A Harada, Y Nagasaki - Advanced drug delivery reviews, 2012 - Elsevier
Recently, colloidal carrier systems have been receiving much attention in the field of drug
targeting because of their high loading capacity for drugs as well as their unique disposition …

Applications of orthogonal “click” chemistries in the synthesis of functional soft materials

RK Iha, KL Wooley, AM Nystrom, DJ Burke… - Chemical …, 2009 - ACS Publications
Applications for advanced functional soft materials that possess precisely engineered
properties and functional groups have been expanding significantly with the development of …