Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

Neuronal plasticity allows the central nervous system to learn skills and remember
information, to reorganize neuronal networks in response to environmental stimulation, and …

Accumulative evidence indicates that microglial cells influence the normal development of
brain synapses. Yet, the mechanisms by which these immune cells target maturating …

In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …

We begin by distinguishing computationalism from a number of other theses that are
sometimes conflated with it. We also distinguish between several important kinds of …

In the past three decades, mounting evidence has revealed that specification of the basic
cortical neuronal classes starts at the time of their final mitotic divisions in the embryonic …

Abstract Development passes through sensitive periods, during which plasticity allows for
genetic and environmental factors to exert indelible influence on the maturation of the …

Autism is a developmental disorder defined by the presence of a triad of communication,
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite …

The CCCTC-binding factor (CTCF) is a key molecule for chromatin conformational changes
that promote cellular diversity, but nothing is known about its role in neurons. Here, we …

Patterned neuronal activity such as spindle bursts in the neonatal cortex is likely to promote
the maturation of cortical synapses and neuronal circuits. Previous work on cats has shown …