Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials

M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022‏ - Elsevier
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases

S Hædersdal, A Andersen, FK Knop… - Nature Reviews …, 2023‏ - nature.com
Insulin and glucagon exert opposing effects on glucose metabolism and, consequently,
pancreatic islet β-cells and α-cells are considered functional antagonists. The intra-islet …

Nutritional ketosis alters fuel preference and thereby endurance performance in athletes

PJ Cox, T Kirk, T Ashmore, K Willerton, R Evans… - Cell metabolism, 2016‏ - cell.com
Ketosis, the metabolic response to energy crisis, is a mechanism to sustain life by altering
oxidative fuel selection. Often overlooked for its metabolic potential, ketosis is poorly …

Understanding the factors that effect maximal fat oxidation

T Purdom, L Kravitz, K Dokladny… - Journal of the …, 2018‏ - Taylor & Francis
Lipids as a fuel source for energy supply during submaximal exercise originate from
subcutaneous adipose tissue derived fatty acids (FA), intramuscular triacylglycerides (IMTG) …

[HTML][HTML] Plasma metabolome profiling of resistance exercise and endurance exercise in humans

T Morville, RE Sahl, T Moritz, JW Helge… - Cell reports, 2020‏ - cell.com
The mechanisms by which exercise benefits human health remain incompletely understood.
With the emergence of omics techniques, map** of the molecular response to exercise is …

[HTML][HTML] Evidence-based supplements for the enhancement of athletic performance

P Peeling, MJ Binnie, PSR Goods… - … journal of sport …, 2018‏ - journals.humankinetics.com
A strong foundation in physical conditioning and sport-specific experience, in addition to a
bespoke and periodized training and nutrition program, are essential for athlete …

Glucagon receptor signaling and glucagon resistance

L Janah, S Kjeldsen, KD Galsgaard… - International journal of …, 2019‏ - mdpi.com
Hundred years after the discovery of glucagon, its biology remains enigmatic. Accurate
measurement of glucagon has been essential for uncovering its pathological hypersecretion …

New insights into the interaction of carbohydrate and fat metabolism during exercise

LL Spriet - Sports medicine, 2014‏ - Springer
Fat and carbohydrate are important fuels for aerobic exercise and there can be reciprocal
shifts in the proportions of carbohydrate and fat that are oxidized. The interaction between …

[HTML][HTML] l-carnitine: Nutrition, pathology, and health benefits

AH Alhasaniah - Saudi Journal of Biological Sciences, 2023‏ - Elsevier
Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

Characterising the muscle anabolic potential of dairy, meat and plant-based protein sources in older adults

SHM Gorissen, OC Witard - Proceedings of the Nutrition Society, 2018‏ - cambridge.org
The age-related loss of skeletal muscle mass and function is caused, at least in part, by a
reduced muscle protein synthetic response to protein ingestion. The magnitude and duration …