Progressive cerebral deposition of the amyloid β-protein (Aβ) in brain regions serving
memory and cognition is an invariant and defining feature of Alzheimer disease. A highly …

The association of the amyloid-β (Aβ) peptide with cellular membranes is hypothesized to be
the underlying phenomenon of neurotoxicity in Alzheimer's disease. Misfolding of proteins …

Interfaces can strongly accelerate or inhibit protein aggregation, destabilizing proteins that
are stable in solution or, conversely, stabilizing proteins that are aggregation-prone …

In this article, we consider the role of heterogeneous nucleation in β‐amyloid aggregation.
Heterogeneous nucleation is more common and occurs at lower levels of supersaturation …

Clarification of the molecular and cellular mechanisms underlying the assembly of amyloid β-
protein (Aβ) into insoluble fibrils in the brain has been one of the biggest challenges in the …

It is widely accepted that the abnormal self-association of amyloid β-protein (Aβ) is central to
the pathogenesis of Alzheimer's disease, the most common form of dementia. Accumulating …

Assembly and deposition of amyloid ß-protein (Aß) is an invariable and fundamental event
in the pathological process of Alzheimer's disease (AD). To decipher the AD pathogenesis …

Age-related alterations of membrane lipids in brain cell membranes together with high blood
cholesterol are considered as major risk factors for Alzheimer's disease. Yet the molecular …

Amyloid fibrils are insoluble, fibrous nanostructures that accumulate extracellularly in
biological tissue during the progression of several human disorders, including Alzheimer's …

Alzheimer's disease (AD) is associated with progressive accumulation of amyloid-β (Aβ)
cross-β fibrils in the brain. Aβ species tightly associated with GM1 ganglioside, a …