Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Navigating the fungal battlefield: Cysteine-rich antifungal proteins and peptides from Eurotiales

J Holzknecht, F Marx - Frontiers in Fungal Biology, 2024 - frontiersin.org
Fungi are ubiquitous in the environment and play a key role in the decomposition and
recycling of nutrients. On the one hand, their special properties are a great asset for the …

[HTML][HTML] Identificación molecular de hongos filamentosos y su potencial biotecnológico

LY SUÁREZ-CONTRERAS… - Biotecnología en el …, 2022 - scielo.org.co
Los hongos filamentosos son organismos frecuentemente utilizados en el desarrollo de
alternativas para resolver desafíos en diferentes sectores productivos. Igualmente …

Differential susceptibility of mycotoxin-producing fungi to distinct antifungal proteins (AFPs)

PV Martínez-Culebras, M Gandía, A Boronat… - Food …, 2021 - Elsevier
The global challenge to prevent fungal spoilage and mycotoxin contamination on foods and
feeds require the development of new antifungal strategies. Filamentous fungi encode …

Potential of Antifungal Proteins (AFPs) to Control Penicillium Postharvest Fruit Decay

M Gandía, A Kakar, M Giner-Llorca, J Holzknecht… - Journal of Fungi, 2021 - mdpi.com
Penicillium phytopathogenic species provoke severe postharvest disease and economic
losses. Penicillium expansum is the main pome fruit phytopathogen while Penicillium …

[HTML][HTML] Phosphatase-degradable nanoparticles: a game-changing approach for the delivery of antifungal proteins

ZB Akkuş-Dağdeviren, A Saleh, C Schöpf… - Journal of Colloid and …, 2023 - Elsevier
Hypothesis Polyphosphate nanoparticles as phosphatase-degradable carriers for
Penicillium chrysogenum antifungal protein (PAF) can enhance the antifungal activity of the …

Small, Cationic Antifungal Proteins from Filamentous Fungi Inhibit Candida albicans Growth in 3D Skin Infection Models

J Holzknecht, S Dubrac, S Hedtrich… - Microbiology …, 2022 - Am Soc Microbiol
The emerging resistance of human-pathogenic fungi to antifungal drugs urges the
development of alternative therapeutic strategies. The small, cationic antifungal proteins …

The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens

PA Fardella, BB Clarke, FC Belanger - Microorganisms, 2023 - mdpi.com
Fungal plant pathogens can present major problems for most crop species. Currently,
control of fungal diseases relies heavily on the use of fungicides. However, there are …

The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans

J Holzknecht, A Kühbacher, C Papp, A Farkas… - Journal of Fungi, 2020 - mdpi.com
Small, cysteine-rich and cationic antimicrobial proteins (AMPs) from filamentous
ascomycetes promise treatment alternatives to licensed antifungal drugs. In this study, we …

[HTML][HTML] Rationally designed antifungal protein chimeras reveal new insights into structure-activity relationship

M Giner-Llorca, FG del Sol, JF Marcos, A Marina… - International journal of …, 2023 - Elsevier
Antifungal proteins (AFPs) are promising antimicrobial compounds that represent a feasible
alternative to fungicides. Penicillium expansum encodes three phylogenetically distinct …