Abstract Objectives: Clinical Research Informatics, an emerging sub-domain of Biomedical
Informatics, is currently not well defined. A formal description of CRI including major …

The United States witnessed a nearly 4‐fold increase in personal health care expenditures
between 1980 and 2010. Despite innovations and obvious benefits to health, participants …

BACKGROUND. Honest broker services are essential for tissue‐and data‐based research.
The honest broker provides a firewall between clinical and research activities. Clinical …

Background High throughput molecular sequencing and increased biospecimen variety
have introduced significant informatics challenges for research biorepository infrastructures …

Ophthalmology researchers are becoming increasingly reliant on protected data sets to find
new trends and enhance patient care. However, there is an inherent lack of trust in the …

Over the past 20 years, imaging informatics has been driven by the widespread adoption of
radiology information and picture archiving and communication and speech recognition …

Biorepository research has introduced significant challenges to biomedical informatics
systems design and implementation. We take a best-of-breed system integrative approach to …

Comparative effectiveness, clinical translational research, and personalized medicine
depend on the accessibility of data and information. This dissertation introduces an ontology …

Data-intensive science applications in areas such as high-energy and particle physics,
bioinformatics, genomics, and healthcare are increasingly using distributed resources for …

Ein zentrales Thema der medizinischen Informatik ist der institutionsübergreifende
Austausch von Patientendaten zwischen den Akteuren des Gesundheitswesens. Die …