Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Cognitive impairment and dementia are burgeoning public health concerns, especially
given the increasing longevity of the global population. These conditions not only affect the …

As aging societies in the western world face a growing prevalence of vascular cognitive
impairment and Alzheimer's disease (AD), understanding their underlying causes and …

Graph-theoretic metrics derived from neuroimaging data have been heralded as powerful
tools for uncovering neural mechanisms of psychological traits, psychiatric disorders, and …

Background and Objectives Information on whether small vessel disease (SVD) reduces life
expectancy is limited. Moreover, the excess mortality risk attributed specifically to SVD …

Background and Objectives Previous studies have linked the MRI measures of perivascular
spaces (PVSs), diffusivity along the perivascular spaces (DTI-ALPS), and free water (FW) to …

Cerebral small vessel disease (SVD), which is highly age-related, is the most common
neuroimaging finding in community-dwelling elderly individuals. In addition to increasing the …

Background To investigate whether structural network disconnectivity is associated with
parkinsonian signs and their progression, as well as with an increased risk of incident …

Background Cerebral small vessel disease (CSVD) is closely related to gait disorders.
Previous studies have found a negative correlation between the severity of MRI white matter …

Intra-vital visualization of deep cerebrovascular structures and blood flow in the aging brain
has been a difficult challenge in the field of neurovascular research, especially when …