Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Radiation exposures at ultrahigh dose rates (UHDRs) at several orders of magnitude greater
than in current clinical radiotherapy (RT) have been shown to manifest differential …

Lung cancer stands as the primary contributor to cancer-related fatalities worldwide,
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …

Cancer cell death is the utmost aim in cancer therapy. Anti-cancer agents can induce
apoptosis, mitotic catastrophe, senescence, or autophagy through the production of free …

Ionizing radiation is often regarded as an element of danger. But, danger responses on the
cellular and molecular level are often beneficial with regard to the induction of anti‐tumor …

Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1) is a
multifunctional enzyme that is essential for maintaining cellular homeostasis. APE1 is the …

In cancer treatments, especially high-dose radiotherapy (HDRT) is applied. Patients
suffering from chronic inflammatory diseases benefit from low-dose radiation therapy …

Cellular senescence is a key process in physiological dysfunction develo** upon aging or
following diverse stressors including ionizing radiation. It describes the state of a permanent …

Inflammation is an important physiological response of the organism to restore homeostasis
upon pathogenic or damaging stimuli. However, the persistence of the harmful trigger or a …