Despite the ability of peripheral nerves to spontaneously regenerate after injury, recovery is
generally very poor. The neurotrophins have emerged as an important modulator of axon …

Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

This is a book on mathematical neuroscience, in which the unifying theme is wavelike
phenomena at multiple spatial and temporal scales. There are already several excellent …

Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative
medicine, with increasing importance in central and peripheral nervous system repair …

Microelectrode arrays (MEAs) find application both in vitro and in vivo to record and
stimulate electrical activity in electrogenic cells such as neurons, cardiomyocytes, pancreatic …

Injured peripheral nerves typically exhibit unsatisfactory and incomplete functional
outcomes, and there are no clinically approved therapies for improving regeneration. Post …

Hypoxic–ischemic encephalopathy (HIE) is a serious condition that could have deleterious
neurological outcomes, such as cerebral palsy, neuromotor disability, developmental …

Background Peripheral nerve injury (PNI) is a worldwide issue associated with severe social
and economic burden. Autologous nerve grafting, the gold standard treatment for peripheral …

Spinal cord injury (SCI) is a profoundly debilitating yet common central nervous system
condition resulting in significant morbidity and mortality rates. Major causes of SCI …

Historically, the field of regenerative medicine has aimed to heal damaged tissue through
the use of biomaterials scaffolds or delivery of foreign progenitor cells. Despite 30 years of …