[HTML][HTML] Minimally invasive versus open thymectomy for thymic malignancies: systematic review and meta-analysis

AJ Friedant, EA Handorf, S Su, WJ Scott - Journal of Thoracic Oncology, 2016 - Elsevier
Complete resection is the standard of care for treatment of thymic malignancies. The use of
minimally invasive surgery remains controversial. We searched online databases and …

[HTML][HTML] Chemotherapy definitions and policies for thymic malignancies

N Girard, R Lal, H Wakelee, GJ Riely… - Journal of Thoracic …, 2011 - Elsevier
METHODS This article represents a broad consensus within the ITMIG community, based on
available underlying evidence. A core workgroup assembled data for discussion based on a …

[HTML][HTML] Thymic carcinoma: a cohort study of patients from the European society of thoracic surgeons database

E Ruffini, F Detterbeck, D Van Raemdonck… - Journal of Thoracic …, 2014 - Elsevier
Introduction: Thymic carcinoma is a rare and aggressive thymic neoplasm. The European
Society of Thoracic Surgeons developed a retrospective database collecting patients …

Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas

N Girard, R Shen, T Guo, MF Zakowski… - Clinical Cancer …, 2009 - aacrjournals.org
Purpose: Thymomas and thymic carcinomas are rare intrathoracic malignancies that can be
invasive and refractory to conventional treatment. Because these tumors both originate from …

Thymomas and thymic carcinomas

DS Ettinger, GJ Riely, W Akerley, H Borghaei… - Journal of the National …, 2013 - jnccn.org
Masses in the anterior mediastinum can be neoplasms (eg, thymomas, thymic carcinomas,
or lung metastases) or non-neoplastic conditions (eg, intrathoracic goiter). Thymomas are …

[HTML][HTML] Comparison of patterns of relapse in thymic carcinoma and thymoma

J Huang, NP Rizk, WD Travis, GJ Riely, BJ Park… - The Journal of thoracic …, 2009 - Elsevier
OBJECTIVE: Thymic carcinomas are considered to be more aggressive than thymomas and
carry a worse prognosis. We reviewed our recent experience with the surgical management …

[HTML][HTML] Imatinib mesylate in patients with WHO B3 thymomas and thymic carcinomas

G Giaccone, A Rajan, R Ruijter, E Smit… - Journal of Thoracic …, 2009 - Elsevier
Thymic malignancies are rare tumors of the mediastinum. c-KIT is highly expressed in thymic
carcinomas (TC) but infrequently in thymomas. Anecdotal experience suggests activity of …

Mutational status of EGFR and KIT in thymoma and thymic carcinoma

K Yoh, Y Nishiwaki, G Ishii, K Goto, K Kubota… - Lung Cancer, 2008 - Elsevier
This study was conducted to evaluate the prevalence of EGFR and KIT mutations in
thymomas and thymic carcinomas as a means of exploring the potential for molecularly …

Sunitinib in metastatic thymic carcinomas: laboratory findings and initial clinical experience

P Ströbel, R Bargou, A Wolff, D Spitzer… - British journal of …, 2010 - nature.com
Background: Thymic carcinoma (TC) is a rare aggressive tumour. Median survival with
current treatments is only 2 years. Sunitinib is a multi-targeted tyrosine kinase inhibitor that …

[HTML][HTML] PI3K as a potential therapeutic target in thymic epithelial tumors

AT Alberobello, Y Wang, FJ Beerkens, F Conforti… - Journal of Thoracic …, 2016 - Elsevier
Abstract Introduction Thymic epithelial tumors (TETs) are rare tumors originating from the
epithelium of the thymus with limited therapeutic options beyond surgery. The pathogenesis …