Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

A high incidence of pregnancy failures occurs in cattle during the second week of pregnancy
as blastocysts transition into an elongated conceptus. This work explored whether …

Cell identity is orchestrated through an interplay between transcription factor (TF) action and
genome architecture. The mechanisms used by TFs to shape three-dimensional (3D) …

This work explored whether a well-characterized recombinant human interleukin-6 (hIL6)
protein will influence in vitro produced (IVP) bovine embryo development and survival after …

Embryonic stem (ES) cells differentiate towards all three germ layers, including cardiac cells
and leukocytes, and may be therefore suitable to model inflammatory reactions in vitro. In …

In mammals, blastocyst-stage trophectoderm (TE) contacts the maternal body at the time 26
of implantation and forms the placenta after implantation, which supports the 27 …

Embryo implantation requires tightly coordinated signaling between the blastocyst and the
endometrium, and is crucial for the establishment of a uteroplacental unit that persists until …

ABSTRACT DNA methylation is traditionally associated with gene silencing, but its causal
relationship and role in sha** cell fate decisions still need to be fully elucidated. Here, we …

IL-6 plays an important role in oogenesis in humans. However, at the preimplantation stage,
IL-6 production and the role in embryo development remain unclear. In this study, IL-6 …

Patogenetski mehanizmi nastanka preterminskog porođaja (PP) su nedovoljno ispitani.
Najčešći razlog PP je inflamacijska reakcija, predominantno po tipu horioamnionitisa, u …