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Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
INTRODUCTION Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …
[HTML][HTML] SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
MG Joyce, WH Chen, RS Sankhala, A Hajduczki… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
Antigen delivery systems: past, present, and future
HJ Ko, YJ Kim - Biomolecules & Therapeutics, 2023 - pmc.ncbi.nlm.nih.gov
The COVID-19 pandemic has increased demand for safe and effective vaccines. Research
to develop vaccines against diseases including Middle East respiratory syndrome …
to develop vaccines against diseases including Middle East respiratory syndrome …
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
HAD King, MG Joyce, I Lakhal-Naouar… - Proceedings of the …, 2021 - pnas.org
Emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …
A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice
SARS-CoV in 2003, SARS-CoV-2 in 2019, and SARS-CoV-2 variants of concern (VOC) can
cause deadly infections, underlining the importance of develo** broadly effective …
cause deadly infections, underlining the importance of develo** broadly effective …
Efficacy of a broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine in nonhuman primates
MG Joyce, HAD King, IE Naouar, A Ahmed… - BioRxiv, 2021 - biorxiv.org
The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants stresses the continued need for next-generation vaccines that confer broad …
variants stresses the continued need for next-generation vaccines that confer broad …
Immunogenicity and neutralizing activity comparison of SARS-CoV-2 spike full-length and subunit domain proteins in young adult and old-aged mice
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be expanding
the pandemic disease across the globe. Although SARS-CoV-2 vaccines were rapidly …
the pandemic disease across the globe. Although SARS-CoV-2 vaccines were rapidly …
[HTML][HTML] Pan-SARS neutralizing responses after third boost vaccination in non-human primate immunogenicity model
KV Kalnin, T Plitnik, M Kishko, D Huang, A Raillard… - Vaccine, 2022 - Elsevier
The emergence of SARS-CoV-2 variants, especially Beta and Delta, has raised concerns
about the reduced protection from previous infection or vaccination based on the original …
about the reduced protection from previous infection or vaccination based on the original …
An adjuvanted SARS-CoV-2 RBD nanoparticle elicits neutralizing antibodies and fully protective immunity in aged mice
Development of affordable and effective vaccines that can also protect vulnerable
populations such as the elderly from COVID-19-related morbidity and mortality is a public …
populations such as the elderly from COVID-19-related morbidity and mortality is a public …