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Chemical glycoproteomics
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …
to studying protein glycosylation, the most widespread and complex form of posttranslational …
Recent advances in the mass spectrometry methods for glycomics and cancer
The review focuses on recent aspects (last three years) of glycosylation analyses that
provide relevant information about cancer. It includes recent development in glycan and …
provide relevant information about cancer. It includes recent development in glycan and …
Cell membrane–camouflaged liposomes for tumor cell–selective glycans engineering and imaging in vivo
The dynamic change of cell-surface glycans is involved in diverse biological and
pathological events such as oncogenesis and metastasis. Despite tremendous efforts, it …
pathological events such as oncogenesis and metastasis. Despite tremendous efforts, it …
Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers
Background Osteoarthritis (OA) is a slowly develo** and debilitating disease, and there
are no validated specific biomarkers for its early detection. To improve therapeutic …
are no validated specific biomarkers for its early detection. To improve therapeutic …
Map** the cancer surface proteome in search of target antigens for immunotherapy
Immune-based therapeutic interventions recognizing proteins localized on the cell surface of
cancer cells are emerging as a promising cancer treatment. Antibody-based therapies and …
cancer cells are emerging as a promising cancer treatment. Antibody-based therapies and …
LncRNA PSMA3‐AS1 promotes cell proliferation, migration, and invasion in ovarian cancer by activating the PI3K/Akt pathway via the miR‐378a‐3p/GALNT3 axis
Z Xu, H **, X Duan, H Liu, X Zhao, S Fan… - Environmental …, 2021 - Wiley Online Library
The crucial roles of the long noncoding RNAs (lncRNAs) in the development of ovarian
cancer (OC) have been extensively studied. According to the prediction result from the …
cancer (OC) have been extensively studied. According to the prediction result from the …
Chemical proteomics to study metabolism, a reductionist approach applied at the systems level
Cellular metabolism encompasses a complex array of interconnected biochemical pathways
that are required for cellular homeostasis. When dysregulated, metabolism underlies …
that are required for cellular homeostasis. When dysregulated, metabolism underlies …
Glycobiology modifications in intratumoral hypoxia: the breathless side of glycans interaction
Post-translational and co-translational enzymatic addition of glycans (glycosylation) to
proteins, lipids, and other carbohydrates, is a powerful regulator of the molecular machinery …
proteins, lipids, and other carbohydrates, is a powerful regulator of the molecular machinery …
Downregulation of circ‐RAPGEF5 inhibits colorectal cancer progression by reducing the expression of polypeptide N‐acetylgalactosaminyltransferase 3 (GALNT3)
D Cheng, F Chu, F Liang, N Zhang… - Environmental …, 2024 - Wiley Online Library
Abstract Background Circular RNA (circRNA) plays a crucial role in the pathogenesis and
progression of colorectal cancer (CRC). However, the current understanding of the …
progression of colorectal cancer (CRC). However, the current understanding of the …
Altered expression of different GalNAc-transferases is associated with disease progression and poor prognosis in women with high-grade serous ovarian cancer
R Sheta, M Bachvarova, M Plante… - International …, 2017 - spandidos-publications.com
Protein glycosylation perturbations are implicated in a variety of diseases, including cancer.
Aberrant glycosylation in cancer is frequently attributed to altered expression of polypeptide …
Aberrant glycosylation in cancer is frequently attributed to altered expression of polypeptide …