Long non-coding RNAs (lncRNAs) are a diverse class of RNAs that engage in numerous
biological processes across every branch of life. Although initially discovered as mRNA-like …

Noncoding RNAs (ncRNAs) accomplish a remarkable variety of biological functions. They
regulate gene expression at the levels of transcription, RNA processing, and translation …

Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …

Homologous recombination is a molecular process that has multiple important roles in DNA
metabolism, both for DNA repair and genetic variation in all forms of life. Generally …

Abstract Model organisms are widely used in research as accessible and convenient
systems to study a particular area or question in biology. Traditionally only a handful of …

Transposons populate the landscape of all eukaryotic genomes. Often considered purely
genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation …

Sexual reproduction and clonality in eukaryotes are mostly seen as exclusive, the latter
being rather exceptional. This view might be biased by focusing almost exclusively on …

The task of information processing, or computation, can be performed by natural and man-
made'devices'. Man-made computers are made from silicon chips, whereas …

The transcriptional networks that regulate embryonic stem (ES) cell pluripotency and lineage
specification are the subject of considerable attention. To date such studies have focused …