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Anti-inflammatory and neuroprotective agents in clinical trials for CNS disease and injury: where do we go from here?
Neurological disorders are major contributors to death and disability worldwide. The
pathology of injuries and disease processes includes a cascade of events that often involve …
pathology of injuries and disease processes includes a cascade of events that often involve …
Effects of disease-modifying therapy on peripheral leukocytes in patients with multiple sclerosis
Modern disease-modifying therapies (DMTs) in multiple sclerosis (MS) have variable modes
of action and selectively suppress or modulate the immune system. In this review, we …
of action and selectively suppress or modulate the immune system. In this review, we …
Considering patient clinical history impacts performance of machine learning models in predicting course of multiple sclerosis
Multiple Sclerosis (MS) progresses at an unpredictable rate, but predictions on the disease
course in each patient would be extremely useful to tailor therapy to the individual needs …
course in each patient would be extremely useful to tailor therapy to the individual needs …
Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
A Fodor-Kardos, ÁF Kiss, K Monostory, T Feczkó - RSC advances, 2020 - pubs.rsc.org
Interferon-beta-1a (IFN-β-1a) can diminish the symptoms of relapsing-remitting multiple
sclerosis. Herein, we prepared sustained drug delivery IFN-β-1a-loaded nanoparticles by a …
sclerosis. Herein, we prepared sustained drug delivery IFN-β-1a-loaded nanoparticles by a …
Nitric oxide involvement in the disability and active disease of multiple sclerosis: Systematic review and meta-analysis
Background Multiple sclerosis (MS) is a chronic and immune-mediated disease of unknown
etiology and leading to a physical and cognitive disability. Different studies suggest that …
etiology and leading to a physical and cognitive disability. Different studies suggest that …
Eighteen-month safety analysis of offspring breastfed by mothers receiving glatiramer acetate therapy for relapsing multiple sclerosis–COBRA study
AI Ciplea, A Kurzeja, S Thiel, S Haben… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Safety data on disease-modifying therapies (DMTs) for relapsing multiple
sclerosis (RMS) during breastfeeding are limited. Objective: Assess safety outcomes for …
sclerosis (RMS) during breastfeeding are limited. Objective: Assess safety outcomes for …
Advanced oxidative protein products role in multiple sclerosis: A systematic review and meta-analysis
Multiple sclerosis (MS) is an autoimmune-mediated disease that damages the central
nervous system. MS pathophysiological features are not entirely understood, but the …
nervous system. MS pathophysiological features are not entirely understood, but the …
Vitamin D changes expression of DNA repair genes in the patients with multiple sclerosis
Oxidative stress (OS) plays an essential role in demyelination and tissue injury related to
pathogenesis of multiple sclerosis (MS). On the other hand, vitamin D (VD) as an antioxidant …
pathogenesis of multiple sclerosis (MS). On the other hand, vitamin D (VD) as an antioxidant …
[HTML][HTML] Potential Crosstalk between the PACAP/VIP Neuropeptide System and Endoplasmic Reticulum Stress—Relevance to Multiple Sclerosis Pathophysiology
M Withana, A Castorina - Cells, 2023 - mdpi.com
Multiple sclerosis (MS) is an immune-mediated disorder characterized by focal
demyelination and chronic inflammation of the central nervous system (CNS). Although the …
demyelination and chronic inflammation of the central nervous system (CNS). Although the …
Antibodies to the RNA binding protein heterogeneous nuclear ribonucleoprotein A1 contribute to neuronal cell loss in an animal model of multiple sclerosis
CD Libner, HE Salapa, C Hutchinson… - Journal of …, 2020 - Wiley Online Library
Neurodegeneration, including loss of neurons and axons, is a feature of progressive forms
of multiple sclerosis (MS). The mechanisms underlying neurodegeneration are mostly …
of multiple sclerosis (MS). The mechanisms underlying neurodegeneration are mostly …