Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials

S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl… - EMBO …, 2023 - embopress.org
Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

The pan-immune system of bacteria: antiviral defence as a community resource

A Bernheim, R Sorek - Nature reviews microbiology, 2020 - nature.com
Viruses and their hosts are engaged in a constant arms race leading to the evolution of
antiviral defence mechanisms. Recent studies have revealed that the immune arsenal of …

Positive and negative aspects of bacteriophages and their immense role in the food chain

SA Ranveer, V Dasriya, MF Ahmad, HS Dhillon… - npj Science of …, 2024 - nature.com
Bacteriophages infect and replicate inside a bacterial host as well as serve as natural bio-
control agents. Phages were once viewed as nuisances that caused fermentation failures …

Mechanisms of action of plant growth promoting bacteria

OS Olanrewaju, BR Glick, OO Babalola - World Journal of Microbiology …, 2017 - Springer
The idea of eliminating the use of fertilizers which are sometimes environmentally unsafe is
slowly becoming a reality because of the emergence of microorganisms that can serve the …

An overview of the public health challenges in diagnosing and controlling human foodborne pathogens

A Elbehiry, A Abalkhail, E Marzouk, AE Elmanssury… - Vaccines, 2023 - mdpi.com
Pathogens found in food are believed to be the leading cause of foodborne illnesses; and
they are considered a serious problem with global ramifications. During the last few …

Phages for phage therapy: isolation, characterization, and host range breadth

P Hyman - Pharmaceuticals, 2019 - mdpi.com
For a bacteriophage to be useful for phage therapy it must be both isolated from the
environment and shown to have certain characteristics beyond just killing strains of the …

Contemporary phage biology: from classic models to new insights

G Ofir, R Sorek - Cell, 2018 - cell.com
Bacteriophages, discovered about a century ago, have been pivotal as models for
understanding the fundamental principles of molecular biology. While interest in phage …

Phage-specific metabolic reprogramming of virocells

C Howard-Varona, MM Lindback, GE Bastien… - The ISME …, 2020 - academic.oup.com
Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …

Secondary bacterial infections in patients with viral pneumonia

P Manohar, B Loh, R Nachimuthu, X Hua… - Frontiers in …, 2020 - frontiersin.org
Pulmonary diseases of viral origin are often followed by the manifestation of secondary
infections, leading to further clinical complications and negative disease outcomes. Thus …

[HTML][HTML] In vitro techniques and measurements of phage characteristics that are important for phage therapy success

T Glonti, JP Pirnay - Viruses, 2022 - mdpi.com
Validated methods for phage selection, host range expansion, and lytic activity
determination are indispensable for maximizing phage therapy outcomes. In this review, we …