A procedure is outlined for comparing dependence potential and acute toxicity across a
broad range of abused psychoactive substances. Tentative results, based on an extensive …

Nitrous oxide (N2O) has been known since the end of the eighteenth century. Today, N2O
plays a huge role as a greenhouse gas and an ozone-depleting stratospheric molecule. The …

The neurobiology of the psychedelic experience is not fully understood. Identifying common
brain network changes induced by both classical (ie, acting at the 5-HT 2 receptor) and non …

Background Neurodevelopmental disorders are increasing in prevalence worldwide.
Previous work suggests that exposure to the environmental air pollutant and greenhouse …

Background Nitrous oxide use is shifting from general anesthesia to sedation and pain
control. Interest in novel uses of nitrous oxide in psychiatry is also growing. Thus …

Despite the longstanding use of nitrous oxide and descriptions of its psychological effects
more than a century ago, there is a paucity of neurobiological investigation of associated …

ABSTRACT Unlabelled Image Background An estimated 35 million Americans experience
significant apprehension about dental procedures, while an additional 10 to 12 million are …

Since 2020, our lab has received blood samples from traffic cases involving suspicion of
driving under the influence of nitrous oxide (N 2 O). While N 2 O analysis by gas …

Inhalant abuse is a serious public health problem throughout the world. The present study
compared the states of intoxication produced by three inhaled anesthetics that represent two …

The subjective, psychomotor and reinforcing effects of nitrous oxide at subanesthetic doses
(30% and 40% in oxygen) were determined in normal healthy volunteers using a choice …