Mining genomes to illuminate the specialized chemistry of life
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
Plant metabolic gene clusters in the multi-omics era
Secondary metabolism in plants gives rise to a vast array of small-molecule natural
products. The discovery of operon-like gene clusters in plants has provided a new …
products. The discovery of operon-like gene clusters in plants has provided a new …
Integrative omics approaches for biosynthetic pathway discovery in plants
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …
approaches for the identification of plant natural product biosynthetic pathways and their …
Plant biosynthetic gene clusters in the context of metabolic evolution
Covering: up to 2022 Plants produce a wide range of structurally and biosynthetically
diverse natural products to interact with their environment. These specialised metabolites …
diverse natural products to interact with their environment. These specialised metabolites …
Elucidation of tropane alkaloid biosynthesis in Erythroxylum coca using a microbial pathway discovery platform
BG Chavez, P Srinivasan, K Glockzin… - Proceedings of the …, 2022 - National Acad Sciences
Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders
of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae) …
of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae) …
Plant cytochrome P450 plasticity and evolution
The superfamily of cytochrome P450 (CYP) enzymes plays key roles in plant evolution and
metabolic diversification. This review provides a status on the CYP landscape within green …
metabolic diversification. This review provides a status on the CYP landscape within green …
Biosynthesis and antifungal activity of fungus-induced O-methylated flavonoids in maize
Fungal infection of grasses, including rice (Oryza sativa), sorghum (Sorghum bicolor), and
barley (Hordeum vulgare), induces the formation and accumulation of flavonoid …
barley (Hordeum vulgare), induces the formation and accumulation of flavonoid …
The lactonase BxdA mediates metabolic specialisation of maize root bacteria to benzoxazinoids
Root exudates contain specialised metabolites that shape the plant's root microbiome. How
host-specific microbes cope with these bioactive compounds, and how this ability affects root …
host-specific microbes cope with these bioactive compounds, and how this ability affects root …
Hordedane diterpenoid phytoalexins restrict Fusarium graminearum infection but enhance Bipolaris sorokiniana colonization of barley roots
Y Liu, D Esposto, LK Mahdi, A Porzel, P Stark… - Molecular Plant, 2024 - cell.com
Plant immunity is a multilayered process that includes recognition of patterns or effectors
from pathogens to elicit defense responses. These include the induction of a cocktail of …
from pathogens to elicit defense responses. These include the induction of a cocktail of …
Promiscuity, a driver of plant cytochrome P450 evolution?
D Werck-Reichhart - Biomolecules, 2023 - mdpi.com
Plant cytochrome P450 monooxygenases were long considered to be highly substrate-
specific, regioselective and stereoselective enzymes, in this respect differing from their …
specific, regioselective and stereoselective enzymes, in this respect differing from their …