Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …

The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

[HTML][HTML] Imbalance of regulatory and cytotoxic SARS-CoV-2-reactive CD4+ T cells in COVID-19

BJ Meckiff, C Ramírez-Suástegui, V Fajardo, SJ Chee… - Cell, 2020 - cell.com
The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …

The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

[HTML][HTML] The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly

F Zhang, D Aschenbrenner, JY Yoo, T Zuo - The Lancet Microbe, 2022 - thelancet.com
The gut mycobiome (fungi) is a small but crucial component of the gut microbiome in
humans. Intestinal fungi regulate host homoeostasis, pathophysiological and physiological …

Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

[HTML][HTML] Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

I Leonardi, IH Gao, WY Lin, M Allen, XV Li, WD Fiers… - Cell, 2022 - cell.com
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …