The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

The fluid mosaic model of Singer and Nicolson (1972) is a commonly used representation of
the cell membrane structure and dynamics. However a number of features, the result of four …

Synaptic vesicle recycling has long served as a model for the general mechanisms of
cellular trafficking. We used an integrative approach, combining quantitative immunoblotting …

Dendritic spines, the postsynaptic compartments of excitatory neurotransmission, have
different shapes classified from 'stubby'to 'mushroom-like'. Whereas mushroom spines are …

Abstract Dynamin-related protein 1 (Drp1) is essential for mitochondrial and peroxisomal
fission. Recent studies propose that Drp1 does not sever but rather constricts mitochondrial …

There is much interest in develo** synthetic analogues of biological membrane channels
with high efficiency and exquisite selectivity for transporting ions and molecules. Bottom-up …

During endocytosis, energy is invested to narrow the necks of cargo-containing plasma
membrane invaginations to radii at which the opposing segments spontaneously coalesce …

The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

Membrane scission is essential for intracellular trafficking. While BAR domain proteins such
as endophilin have been reported in dynamin-independent scission of tubular membrane …

The endosomal sorting complexes required for transport (ESCRTs) catalyze reverse-
topology scission from the inner face of membrane necks in HIV budding, multivesicular …