From central to specialized metabolism: An overview of some secondary compounds derived from the primary metabolism for their role in conferring nutritional and …

DM Pott, S Osorio, JG Vallarino - Frontiers in plant science, 2019 - frontiersin.org
Fruit flavor and nutritional characteristics are key quality traits and ones of the main factors
influencing consumer preference. Central carbon metabolism, also known as primary …

Data analysis strategies for targeted and untargeted LC-MS metabolomic studies: Overview and workflow

E Gorrochategui, J Jaumot, S Lacorte… - TrAC Trends in Analytical …, 2016 - Elsevier
Data analysis is a very challenging task in LC-MS metabolomic studies. The use of powerful
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …

The tomato pan-genome uncovers new genes and a rare allele regulating fruit flavor

L Gao, I Gonda, H Sun, Q Ma, K Bao, DM Tieman… - Nature …, 2019 - nature.com
Modern tomatoes have narrow genetic diversity limiting their improvement potential. We
present a tomato pan-genome constructed using genome sequences of 725 …

Metabolomics by gas chromatography–mass spectrometry: Combined targeted and untargeted profiling

O Fiehn - Current protocols in molecular biology, 2016 - Wiley Online Library
Gas chromatography–mass spectrometry (GC‐MS)–based metabolomics is ideal for
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …

[HTML][HTML] Variability of single bean coffee volatile compounds of Arabica and robusta roasted coffees analysed by SPME-GC-MS

N Caporaso, MB Whitworth, C Cui, ID Fisk - Food Research International, 2018 - Elsevier
We report on the analysis of volatile compounds by SPME-GC-MS for individual roasted
coffee beans. The aim was to understand the relative abundance and variability of volatile …

CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets

C Kuhl, R Tautenhahn, C Bottcher, TR Larson… - Analytical …, 2012 - ACS Publications
Liquid chromatography coupled to mass spectrometry is routinely used for metabolomics
experiments. In contrast to the fairly routine and automated data acquisition steps …

Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics

WB Dunn, A Erban, RJM Weber, DJ Creek, M Brown… - Metabolomics, 2013 - Springer
Metabolomics has advanced significantly in the past 10 years with important developments
related to hardware, software and methodologies and an increasing complexity of …

NMR-based metabolomic analysis of plants

HK Kim, YH Choi, R Verpoorte - Nature protocols, 2010 - nature.com
Nuclear magnetic resonance (NMR)-based metabolomics has many applications in plant
science. Metabolomics can be used in functional genomics and to differentiate plants from …

Highly sensitive feature detection for high resolution LC/MS

R Tautenhahn, C Böttcher, S Neumann - BMC bioinformatics, 2008 - Springer
Background Liquid chromatography coupled to mass spectrometry (LC/MS) is an important
analytical technology for eg metabolomics experiments. Determining the boundaries …

Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry

RCH De Vos, S Moco, A Lommen, JJB Keurentjes… - Nature protocols, 2007 - nature.com
Untargeted metabolomics aims to gather information on as many metabolites as possible in
biological systems by taking into account all information present in the data sets. Here we …