The presence of cell and tissue barriers together with the low biomembrane permeability of
various therapeutics often hampers systemic drug distribution; thus, most of the available …

The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …

Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

The delivery of drugs via transdermal routes is an attractive approach due to ease of
administration, bypassing of the first-pass metabolism, and the large skin surface area …

Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …

Combinatorial phage library is a powerful research tool for high-throughput screening of
protein interactions. Of all available molecular display techniques, phage display has proven …

Cell-penetrating peptides (CPPs) have been previously shown to be powerful transport
vector tools for the intracellular delivery of a large variety of cargoes through the cell …

Transdermal drug delivery has made an important contribution to medical practice, but has
yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections …

Conspectus One of the recent hot topics in peptide-related chemical biology research is the
potential of cell-penetrating peptides (CPPs). Owing to their ability to deliver exogenous …

Previous cell-penetrating peptides (CPPs) generally have low cytosolic delivery efficiencies,
because of inefficient endosomal escape. In this study, a family of small, amphipathic cyclic …