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Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants
C Liu, H Yu, B Zhang, S Liu, C Liu, F Li, H Song - Biotechnology Advances, 2022 - Elsevier
Biosensors have been widely used as cost-effective, rapid, in situ, and real-time analytical
tools for monitoring environments. The development of synthetic biology has enabled …
tools for monitoring environments. The development of synthetic biology has enabled …
Biosynthesis of monoterpenoid and sesquiterpenoid as natural flavors and fragrances
H Jiang, X Wang - Biotechnology Advances, 2023 - Elsevier
Terpenoids are a large class of plant-derived compounds, that constitute the main
components of essential oils and are widely used as natural flavors and fragrances. The …
components of essential oils and are widely used as natural flavors and fragrances. The …
Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals
X Wan, F Volpetti, E Petrova, C French… - Nature chemical …, 2019 - nature.com
Cell-based biosensors have great potential to detect various toxic and pathogenic
contaminants in aqueous environments. However, frequently they cannot meet practical …
contaminants in aqueous environments. However, frequently they cannot meet practical …
Transcription-factor-based biosensor engineering for applications in synthetic biology
Transcription-factor-based biosensors (TFBs) are often used for metabolite detection,
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
Synthetic biology enables programmable cell‐based biosensors
M Hicks, TT Bachmann, B Wang - ChemPhysChem, 2020 - Wiley Online Library
Cell‐based biosensors offer cheap, portable and simple methods of detecting molecules of
interest but have yet to be truly adopted commercially. Issues with their performance and …
interest but have yet to be truly adopted commercially. Issues with their performance and …
Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast
ML Skjoedt, T Snoek, KR Kildegaard… - Nature chemical …, 2016 - nature.com
Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk
and fine chemicals. Yet the screening of libraries of cellular designs to identify best …
and fine chemicals. Yet the screening of libraries of cellular designs to identify best …
International union of basic and clinical pharmacology CXIII: Nuclear receptor superfamily—Update 2023
The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …
gene network programs involved in a wide range of physiologic processes. This review will …
Engineered CRISPRa enables programmable eukaryote-like gene activation in bacteria
Transcriptional regulation by nuclease-deficient CRISPR/Cas is a popular and valuable tool
for routine control of gene expression. CRISPR interference in bacteria can be reliably …
for routine control of gene expression. CRISPR interference in bacteria can be reliably …
Design of a genetically encoded biosensor to establish a high-throughput screening platform for L-cysteine overproduction
Metabolic engineering seeks to rewire the metabolic network of cells for the efficient
production of value-added compounds from renewable substrates. However, it remains …
production of value-added compounds from renewable substrates. However, it remains …
Synthetic biology for manipulating quorum sensing in microbial consortia
Bacteria exist as communities in diverse multispecies environments. Quorum sensing, a
process for cell–cell communication, allows individual bacteria to glean information about …
process for cell–cell communication, allows individual bacteria to glean information about …