In patients with schizophrenia neuroimaging studies have revealed global differences with
some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion …

Background: The fornix is the primary axonal tract of the hippocampus, connecting it to
modulatory subcortical structures. This review reveals that fornix damage causes cognitive …

Importance Accumulating evidence supports the hypothesis that cerebral white matter
abnormalities are involved in the pathophysiology of schizophrenia; however, findings from …

Schizophrenia is a debilitating psychiatric disorder characterized by positive, negative and
cognitive symptoms. Despite more than a century of research, the neurobiological …

Background Although most patients can recover from SARS-CoV-2 infection during the short-
term, the long-term effects of COVID-19 on the brain remain explored. Functional MRI (fMRI) …

Schizophrenia has long been hypothesized to result from a disconnection syndrome due to
a disruption of the association fibers of the brain. However, only with the advent of in vivo …

Background Diffusion tensor imaging (DTI) has been widely used in psychiatric research
and has provided evidence of white matter abnormalities in first episode schizophrenia …

Background Abnormal white matter integrity has been reported among first episode
schizophrenia patients. However, findings on whether it can be reversed by short-term …

Voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) are the most
implemented methodologies to detect alterations of both gray and white matter (WM) …

Background Disrupted white matter (WM) integrity is the pathological hallmark of
schizophrenia. Previous studies have reported the cognitive deficits that are associated with …