Owing to the diversity and ease of preparation of nanomaterials, the rational nanocarriers
with a rational design have become increasingly popular in medical researches. Although …

Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …

Cloning of the sodium iodide symporter (NIS) 25 years ago has opened an exciting chapter
in molecular thyroidology with the characterization of NIS as one of the most powerful …

New treatment strategies are urgently needed for glioblastoma (GBM)—a tumor resistant to
standard-of-care treatment with a high risk of recurrence and extremely poor prognosis …

Purpose: Mesenchymal stem cells (MSC) have emerged as cellular-based vehicles for the
delivery of therapeutic genes in cancer therapy based on their inherent tumor-homing …

Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use
NIS as a powerful theranostic transgene. Novel gene therapy strategies rely on image …

Sodium iodide symporter (NIS) gene transfer for active accumulation of iodide in tumor cells
is a powerful theranostic strategy facilitating both diagnostic and therapeutic application of …

Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising
new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide …

Background: Several clinical and experimental studies have implicated thyroid hormones in
cancer progression. Cancer-relevant effects, including stimulation of tumor growth and new …