The purpose of this article is to review the status and limitations of anatomic tumor response
metrics including the World Health Organization (WHO) criteria, the Response Evaluation …

New technologies for imaging molecules, particularly optical technologies, are increasingly
being used to understand the complexity, diversity and in vivo behaviour of cancers.'Omic' …

Medical imaging technologies have undergone explosive growth over the past few decades
and now play a central role in clinical oncology. But the truly transformative power of …

Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …

Purpose: We investigated whether inhibition of interleukin 6 (IL-6) has therapeutic activity in
ovarian cancer via abrogation of a tumor-promoting cytokine network. Experimental Design …

Quantitative analysis can potentially improve the accuracy and consistency of 18F-FDG PET,
particularly for the assessment of tumor response to treatment. Although not without …

Tumour responses to treatment are still largely assessed from imaging measurements of
reductions in tumour size. However, this can take several weeks to become manifest and in …

Multimodality imaging, as represented by its greatest exponent, PET/CT, has a firm place in
the evaluation of a patient presenting with cancer. With 18F-FDG, PET/CT is rapidly …

OBJECTIVE: To determine the overall survival and relative effect of multiple prognostic
variables in cohorts of patients with advanced-stage ovarian cancer treated with platinum …

Imaging has become an indispensable tool in the study of cancer biology and in clinical
prognosis and treatment. The rapid advances in high resolution fluorescent imaging at …